These Pizza Enchiladas with Ground Beef combine the flavors of cheesy pizza and hearty enchiladas in one easy family-friendly dinner. Loaded with seasoned beef, pepperoni, pizza sauce, and melted cheese, they’re perfect for busy weeknights.

Pizza Enchiladas with Ground Beef

If your family loves pizza and Mexican-inspired comfort food, these Pizza Enchiladas with Ground Beef are the perfect fusion recipe. Soft tortillas are filled with seasoned ground beef, pepperoni, and plenty of cheese, then rolled up, topped with pizza sauce, and baked until hot and bubbly.

This easy casserole-style meal delivers all the flavors of your favorite pizza in a fun and satisfying new way.

Why You’ll Love This Recipe

Combines pizza and enchilada flavors
Family-friendly and kid-approved
Easy weeknight dinner
Loaded with cheese and savory beef
Great for meal prep
Ready in under an hour

Preparation Time

Prep Time: 15 minutes
Cook Time: 25 minutes
Total Time: 40 minutes

Servings

Serves 6

Ingredients

For the Filling

1 pound ground beef
1 small onion, finely diced
2 cloves garlic, minced
1 teaspoon Italian seasoning
1/2 teaspoon salt
1/4 teaspoon black pepper
1 cup shredded mozzarella cheese
1/2 cup mini pepperoni slices

For Assembly

8 medium flour tortillas
2 cups pizza sauce
2 cups shredded mozzarella cheese
1/2 cup shredded cheddar cheese
1/4 cup grated Parmesan cheese

Optional Toppings

Sliced black olives
Diced bell peppers
Mushrooms
Chopped parsley
Crushed red pepper flakes

Equipment Needed

Large skillet
9×13-inch baking dish
Mixing spoon
Measuring cups and spoons
Aluminum foil (optional)

Step-by-Step Directions

Step 1: Preheat the Oven

Preheat your oven to 375°F (190°C).

Lightly grease a 9×13-inch baking dish.

Step 2: Cook the Ground Beef

Heat a large skillet over medium heat.

Add the ground beef and cook until browned, breaking it apart as it cooks.

Drain excess grease if necessary.

Step 3: Add Seasonings

Add the diced onion and cook for 3–4 minutes until softened.

Stir in the garlic, Italian seasoning, salt, and black pepper.

Cook for 1 minute until fragrant.

Remove from heat.

Step 4: Prepare the Filling

Mix into the beef mixture:

1 cup mozzarella cheese
Mini pepperoni slices

Stir until evenly combined.

Step 5: Fill the Tortillas

Spread a small amount of pizza sauce on the bottom of the baking dish.

Place a tortilla on a flat surface.

Add a portion of the beef mixture down the center.

Roll tightly and place seam-side down in the baking dish.

Repeat with the remaining tortillas.

Step 6: Add Sauce and Cheese

Pour the remaining pizza sauce evenly over the enchiladas.

Top with:

Remaining mozzarella cheese
Cheddar cheese
Parmesan cheese

Add any optional toppings if desired.

Step 7: Bake

Bake uncovered for 20–25 minutes, or until the cheese is melted and bubbly.

For extra browning, broil for 1–2 minutes at the end of cooking.

Step 8: Rest and Serve

Allow the enchiladas to rest for 5 minutes before serving.

Garnish with parsley or crushed red pepper flakes if desired.

Serving Suggestions

Serve these Pizza Enchiladas with:

Garlic bread
Caesar salad
Roasted vegetables
Coleslaw
Fresh fruit salad

Recipe Tips

Use lean ground beef for less grease.
Add cooked sausage for extra pizza flavor.
Customize with your favorite pizza toppings.
Don’t overfill the tortillas to prevent tearing.
Let the dish rest before serving for easier slicing.

Storage Instructions

Refrigerator

Store leftovers in an airtight container for up to 4 days.

Freezer

Freeze baked enchiladas for up to 2 months.

Thaw overnight in the refrigerator before reheating.

Reheating

Warm in a 350°F (175°C) oven until heated through or microwave individual portions.

Variations

Supreme Pizza Enchiladas

Add mushrooms, bell peppers, onions, and olives.

Meat Lover’s Version

Mix ground beef with cooked sausage and bacon.

Chicken Pizza Enchiladas

Replace ground beef with shredded cooked chicken.

Final Thoughts

Pizza Enchiladas with Ground Beef are a fun and delicious mash-up that brings together two comfort food favorites. With savory beef, gooey cheese, pizza sauce, and soft tortillas, this easy baked dish is sure to become a family favorite for busy weeknights and casual gatherings alike.